Researchers identify how brain circuits in mice amplify sensory prediction errors through a unique interaction between the neocortex and thalamus, shedding light on mechanisms that may contribute to ASDs and SSDs.
Scientists at the Sainsbury Wellcome Centre at UCL have discovered how the neocortex and thalamus work together to detect discrepancies between what animals expect from their environment and actual events. These prediction errors are implemented by selective boosting of unexpected sensory information. These findings enhance our understanding of predictive processing in the brain and could offer insights into how brain circuits are altered in autism spectrum disorders (ASDs) and schizophrenia spectrum disorders (SSDs).
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