A century ago, science’s understanding of the brain was primitive, like astronomy before telescopes. Certain brain injuries were known to cause specific problems, like loss of speech or vision, but those findings offered a fuzzy view.

Anatomists had identified nerve cells, or neurons, as key components of the brain and nervous system. But nobody knew how these cells collectively manage the brain’s sophisticated control of behavior, memory or emotions. And nobody knew how neurons communicate, or the intricacies of their connections. For that matter, the research field known as neuroscience — the science of the nervous system — did not exist, becoming known as such only in the 1960s.

Over the last 100 years, brain scientists have built their telescopes. Powerful tools for peering inward have revealed cellular constellations. It’s likely that over 100 different kinds of brain cells communicate with dozens of distinct chemicals. A single neuron, scientists have discovered, can connect to tens of thousands of other cells.

Yet neuroscience, though no longer in its infancy, is far from mature.

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