We have no idea what dark matter is. Most attempts to unravel the mystery entail trying to directly detect primordial dark matter particles as they stream by Earth. But it is, in principle, possible to produce dark matter particles in colliders. Until now, bounds from direct detection have been stronger than such collider searches. Now, the ATLAS collaboration at the LHC reports in Physical Review Letters that it has used the absence of a certain type of such collider production to place the strongest constraints yet on some models of dark matter.
If dark matter consists of weakly interacting massive particles (WIMPs), which couple to protons and neutrons, then these particles have some chance of scattering off nuclei in one of the many underground direct dark matter detectors. Nuclei are made of protons and neutrons, which are in turn made of quarks. Think of the process as WIMP + quark goes to WIMP + quark