Take a fine strand of silica fiber, attach it at each end to a slow-turning motor, gently torture it over an unflickering flame until it just about reaches its melting point and then pull it apart. The middle will thin out like a piece of taffy until it is less than half a micron across—about 200 times thinner than a human hair.
That, according to researchers at the Joint Quantum Institute at the University of Maryland, is how you fabricate ultrahigh transmission optical nanofibers, a potential component for future quantum information devices, which they describe in AIP Publishing's journal AIP Advances.