Gene therapy in theory implies the administration of healthy genetic components into an organism with the aim to cure a disease. Conventionally, it is applied or at least proposed to be applied in the treatment of incurable chronic diseases like cancer, Alzheimer's disease and other brain disorders. But what happens if gene therapy is used to regress the effects of aging or, in other terms, achieve immortality?
Though it sounds too sci-fi and non pragmatic, some people have already started experimenting with the notion. Elizabeth Parrish, who earlier used to work for software companies in Seattle, made the headlines after she voluntarily took gene therapy to cure "aging," Wired reported.
Of course, aging is not a disease. However, as time passes, our body, its miniscule cells and the organelles and biomolecules present inside it (including DNA) get damaged. The wear and tear of these subcellular components is inflicted on the overall physiology of the body. This is why people tend to develop certain age-related diseases.
Scientists have proposed that the age-related DNA damage can be reversed by restricting the shortening of telomeres. Back in 2015, Parrish voluntarily tested the very same telomerase gene therapy on herself. By that time scientists have indicated that the said therapy is capable of increasing longevity in worms and mice. Its human application was and still is restricted due to ethical concerns.
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