Preliminary research results for the NASA Twins Study debuted at NASA's Human Research Program's annual Investigators' Workshop in Galveston, Texas the week of January 23. NASA astronaut Scott Kelly returned home last March after nearly one year in space living on the International Space Station. His identical twin brother, Mark, remained on Earth.
Researchers found this to be a great opportunity for a nature versus nurture study, thus the Twins Study was formed. Using Mark, a retired NASA astronaut, as a ground-based control subject, ten researchers are sharing biological samples taken from each twin before, during and after Scott's mission. From these samples, knowledge is gained as to how the body is affected by extended time in space. These studies are far from complete. Additional research analysis is in process.
Mike Snyder, the Integrated Omics investigator, reported altered levels of a panel of lipids in Scott (the flight twin) that indicate inflammation. Additionally, there was an increased presence of 3-indolepropionic (IPA) in Mark (the ground-based twin). This metabolite is known to be produced only by bacteria in the gut and is being investigated as a potential brain antioxidant therapeutic. IPA is also known to help maintain normal insulin activity to regulate blood sugar after meals.
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