The Pentagon’s research and development division, DARPA—the creative force behind the internet and GPS—retooled itself three years ago to create a new office dedicated to unraveling biology’s engineering secrets. The new Biological Technologies Office (BTO) has a mission to “harness the power of biological systems” and design new defense technology. Over the past year, with a budget of about $296 million, it has been exploring challenges including memory improvement, human–machine symbiosis and speeding up disease detection and response.

DARPA, or the Defense Advanced Research Projects Agency, is hoping for some big returns. The director of its BTO, neuroprosthetic researcher Justin Sanchez, recently spoke with Scientific American about what to expect from his office in 2017, including work on neural implants to aid healthy people in their everyday lives and other advances that he says will “change the game” in medicine.

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